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International Agency for Standards and Ratings honors Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye with Max Planck Research Award-2015 in Food Science for great scientific contribution
04 April, 2015, Nigeria, USA NEWS CORP
Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye are one of Biochemistry's leading celebrity, known for leadership skills and breakthrough research potential. Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye starred in Biochemistry. Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye made International news headlines while IASR announced them among World’s 500 Most Influential Biochemist for Year 2015 on Earth. Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye earned Max Planck Research Award-2015 in Food Science. Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye from Nigeria made a historical victory over the international competition and won Max Planck Research Award-2015 in Food Science. Their research was highlighted in international media and gathered a large worldwide attention in scientific circles while it appeared in world's most read journal 'International Journal of Biochemistry'. In their report on Anti-dysentery Effect of Milled Fermented Maize (“Ogi”) in Escherichia coli Infected Albino Rats they mention that Anti-dysentery effects of uncooked milled, fermented maize (known as “ogi” in Southwestern Nigeria), were investigated in Escherichia coli infected albino rats. “Ogi” was prepared by fermentation of white maize grains for 5 days; wet milled, sieved and allowed to settle for 24 hours. Dysentery was precipitated in albino rats by infection with the pure culture of E. coli. Frequency of blood stool was determined by counting fecal spots on absorbent paper before and after treatment with “ogi”. Physicochemical analysis of “ogi”, comprising titratable acidity, pH 0 and phytochemical screening, was also carried out. Result indicated that 100 mg/kg b.w., 200 mg/kg. b.w. and 400 mg/kg b.w. of “ogi” reduced the number of fecal spots by 48.4%, 80.2% and 96.9%, respectively. Physicochemical analysis revealed that “ogi” had pH of 3.51; titratable acidity of 42.4% lactic acid and presence of alkaloids, saponins, cardiac glycosides and phlobatannins. Dose-dependent therapeutic potency against dysentery has been manifested by “ogi”, most likely aided by its high acidity, presence of lactic acid bacteria and their secondary metabolities, as well as the phytochemicals present in “ogi”. This could be a very simple and cheap solution to the ravaging problem of dysentery in poor families of many developing countries. Under their leadership the research area is surely likely to expand beyond the horizons. It will be worthy to explore the further potential under their legacy. Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye as valuable intellectuals for the country offer exclusive opportunities for scholars around the world. One of the most attractive weightage for Nigeria is to have the awardees for promotion of the concerned scientific discipline for the benefit of its civilians. Thus Nigeria which has excellent track record to produce brain storming intellectuals, has offered a new extension in terms of Osheke Shekins Okere, Samuel Omolabi Adeyemo, Moses Dele Adams and Joshua Omoniyi Kolawole Abioye to world. Available evidence from the present study indicated that the milled fermented maize (“Ogi”) possess anti-dysentery activity. In view of the high prevalence of diarrheal diseases in developing countries and its ravaging effect particularly on children, a very simple and cheap treatment in raw “Ogi” may be an effective solution. Its possible multi-action approach through production of acid environment and various antibacterial agents may also be promising in solving the problem of drug resistance which E. coli quickly acquires. The present study only investigated the anti-dysentery activity of milled fermented maize (“Ogi”) in Escherichia coli infected albino rats. It did not determine the lethal dose (LD50) of “ogi” as well as its possible toxicological implications. The study could not isolate and characterize the bioactive anti-dysentery agent in “ogi” using column chromatography, gas chromatography/mass spectrometry (GC/MS) or High Performance Liquid Chromatography (HPLC). Histology of the tissues was not also carried out. For further studies, the milled fermented maize (“Ogi”) should be isolated and characterized to obtain the bioactive agents as well as provide its possible molecular mechanism of action. Toxicity study should be done on selected tissues of animals to determine functional toxicity. Further studies should carry out histology of tissues which would provide information on whether the extract has the structural toxicity or not. Authors recommend that research grant should be given to researchers to improve on existing findings in Science and Technology. They declare that this study was not financially supported by any research institute, but by the authors. They acknowledge the contributions of Department of Biochemistry, Bingham University, Karu, Nasarawa state, Nigeria.This work was carried out in collaboration between all authors. All authors read and approved the final manuscript.
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