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Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S. are conferred with Max Planck Research Award-2015 in Biochemistry
Latest updated on 08 April, 2015, India, USA NEWS CORP
In terms of Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S., India has secured valuable assets for its generations. Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S.marked a milestone history while cracking international meritorious competition. India has witnessed World’s 500 Most Influential Biochemist for Year 2015 on Earth in terms of Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S.. Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S., given new leadership to world, marked history on international level. Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S. are awarded with Max Planck Research Award-2015 in Biochemistry.
Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S. from India made a historical victory over the international competition and won Max Planck Research Award-2015 in Biochemistry. Their research was highlighted in international media and gathered a large worldwide attention in scientific circles while it appeared in world's most read journal 'International Journal of Biochemistry'. In their report on Correlation of Ischemia Modified Albumin and Advanced Oxidation Protein Products with lipid profile: A Possible link to cardiovascular diseases they mention that Aim: To evaluate the presence of a correlation between Ischemia Modified Albumin (IMA) and Advanced Oxidation Protein Products (AOPP) to cardiovascular diseases. Study design: Our study was designed to evaluate any link between the levels of IMA and AOPP with other risk factors known to increase risk of cardiac diseases (such as lipid profile). Place and duration of the study: This study was conducted by including the patients visiting Father Muller Medical College Hospital, Mangalore, Karnataka, India. The study was conducted for one year from May 2012 to April 2013. Methodology: A total of 151 participants were categorized into normal, prehypertension and hypertension groups. They were assessed for their levels of AOPP and IMA, and then these values were correlated to various other basic parameters. Results: On a whole, when the results of all the three groups were combined and AOPP correlated with the BMI, lipid profile values and IMA, a significant positive correlation (P<0.05) was seen with BMI, LDL (bad cholesterol), Triglycerides, TCHOL: HDL ratio, and NONHDL. Conclusion: The increase in IMA and AOPP levels indicate a positive correlation with most of the lipid profile values, which are known risk factors in cardiovascular diseases. Under their leadership the research area is surely likely to expand beyond the horizons. It will be worthy to explore the further potential under their legacy. Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S. as valuable intellectuals for the country offer exclusive opportunities for scholars around the world. One of the most attractive weightage for India is to have the awardees for promotion of the concerned scientific discipline for the benefit of its civilians. Thus India which has excellent track record to produce brain storming intellectuals, has offered a new extension in terms of Arun Kumar K., Sheila Uthappa, Sudarshan Surendran, Avinash S.S., Sucharitha Suresh and Sushitha E.S. to world.
This study shows the possible direct correlation of AOPP levels to those of BMI, levels of LDL, TG, TCHOL, TCHOL/HDL, and IMA. AOPP or the advanced oxidation protein products are the modified proteins that might have a positive correlation with LDL, TG and other parameters used in the study. This shows that accumulation of AOPP or the formation of the same could relatively increase the levels of LDL and could indirectly lead to cardiac disorders. Such understandings with respect to AOPP could possibly enhance the understanding of the role of AOPP internally. These studies also provide a better understanding of the role of these AOPPs formed in various disease conditions. Oxidative stress induced protein modification product AOPP had direct correlation with risk factors of cardiovascular risk factors such as BMI, LDL, Total Cholesterol across the group. IMA the established marker of myocardial ischemia on the other hand, does not show the same correlation with the risk factors as well as AOPP indicating that mechanism of formation of AOPP may be different from that of IMA. Between the groups with difference in BP, AOPP and IMA have no much difference in correlation with risk factors. Limitation of this study is that groups divided based on BP contain the other risk factors used which might also influence the level of AOPP and IMA. Because of the highly prevalent presence of risk factors of cardiovascular diseases, in order to study the correlation of individual risk factor with IMA and AOPP, it is important to carry out studies with a large sample size.
Such studies, if carried out with a large sample size would provide more clarity regarding the significant correlations between the various parameters.
The authors feel that such studies linking the different aspects of even the well known diseases and the factors linking to smaller contributions from other parameters should be encouraged by the funding agencies to get a better understanding of such diseases.
Kundapura Arun Kumar: Designed the study, wrote the protocol, and performed the analysis and literature search. Sheila Uthappa: Guided in designing the study and writing the protocol. Sudarshan Surendran: Literature search and wrote the first draft of the manuscript. Avinash S.S.: Helped in analysis. Sucharitha Suresh: Helped in analysis. Sushitha E.S.: Performed the statistical analysis
The authors wish to acknowledge the support and encouragement by the management of Father Muller Medical College. We are grateful to Rev. Fr. Patrick Rodrigues, Director; Rev. Fr. Ravi Rudolph D’Sa, Administrator; Dr. JP Alva, Dean, and Dr. Malathi M., Professor and Head of Biochemistry. You can share this News URL on Facebook or your Social Media Site/ blog. USA NEW SCORP If you have a news you can Submit your News in Comment box> Join us as Journalist > News Content purchase > Corrections > Copyright > Place a Classified Ad > Sell Your Home > Sell Your Business > Commercial Real Estate Ads > Advertise with us > Recruitment & Career Ads > Franchising > Advertise Locally > Contact us > plojindexing@gmail.com
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