Thursday, 21 May 2015

Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. led India to Michael Faraday Research Award-2015 in Biochemistry as World’s 500 Most Influential Biochemists




Breaking News: Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. led India to Michael Faraday Research Award-2015 in Biochemistry as World’s 500 Most Influential Biochemists




Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. led India to Michael Faraday Research Award-2015 in Biochemistry as World’s 500 Most Influential Biochemists


22 May, 2015, India, USA NEWS CORP

 Alkaline phosphatase, diabetic nephropathy, gamma glutamyl transferase, lactate dehydrogenase, urinary enzymes, International Journal of Biochemistry, Photon Journal,  Photon Foundation, sslc result, sslc result 2015 tamil nadu, tnresults.nic.in 10th result 2015, 10 th result, sslc results, eamcet results 2015, ap eamcet, ap eamcet results, eamcet results, eamcet 2015, Tanu Weds Manu Returns,  Monosodium Glutamate (MSG) in a sample of MAGGI Noodles, nestle Alkaline phosphatase, diabetic nephropathy, gamma glutamyl transferase, lactate dehydrogenase, urinary enzymes International Journal of Biochemistry Photon Journal  Photon Foundation Alkaline phosphatase, diabetic nephropathy, gamma glutamyl transferase, lactate dehydrogenase, urinary enzymes International Journal of Biochemistry Photon Journal  Photon Foundation Alkaline phosphatase, diabetic nephropathy, gamma glutamyl transferase, lactate dehydrogenase, urinary enzymes International Journal of Biochemistry Photon Journal  Photon Foundation Alkaline phosphatase, diabetic nephropathy, gamma glutamyl transferase, lactate dehydrogenase, urinary enzymes International Journal of Biochemistry Photon Journal  Photon Foundation Alkaline phosphatase, diabetic nephropathy, gamma glutamyl transferase, lactate dehydrogenase, urinary enzymes International Journal of Biochemistry Photon Journal  Photon Foundation

Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M., given the rock star fame in Biochemistry, as declared among World’s 500 Most Influential Biochemists for Year 2015 on Earth. In a worldwide meritorious competition, Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. grabbed the world’s prestigious Michael Faraday Research Award-2015 in Biochemistry. Representing the great legacy of India, Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. established the matter of proud to civilians of India. International Media is now seriously looking towards India, since Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. made a remarkable historical achievement. Biochemists are ensured that under the leadership of Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M., millions of emerging intellectuals would be benefited and inspired around the world.

Mr. Laxman Pokhrel is qualified with M.Sc Degree in Medical Laboratory Technology. He is an alumnus of Father Muller Medical College, Mangalore. As a postgraduate student he was actively involved in research, and was trained in use of analytical equipment and Clinical Biochemistry Laboratory. He is working as a Biochemistry, Bharosa Hospital, Kathmandu.

Mr. Mohamed Rafi is qualified with M.Sc Degree in Medical Laboratory Technology. He is an alumnus of Father Muller Medical College, Mangalore. As a postgraduate student he was actively involved in research, and was trained in use of analytical equipment and Clinical Biochemistry Laboratory. Mr. Rafi is working as the Biochemist in charge of AJ Metropolis Laboratory, Mangalore.

Dr. Shivashankara A.R. is Associate Professor of Biochemistry at Father Muller Medical College, Mangalore. He is a PhD in Biochemistry, and an alumnus of Manipal University. He has 17 years of experience in teaching medical students. He has vast experience in research, and has over 30 research papers to his credit. Dr. Shivashankara is the author of 14 chapters in books on “herbal medicines, and bioactive dietary principles in prevention of diseases”, published by Academic Press. He is a recognized PhD and post graduate guide. He is the Quality Manager of NABL-accredited Father Muller Medical College Hospital Laboratory, Mangalore. His areas of research include salivary diagnostics, urinary biochemical parameters in diabetes mellitus, and alcohol biomarkers.

Dr. Avinash is MBBS, MD (Biochemistry)-qualified professional with 6 years of experience in teaching medical students. He is an alumnus of JN Medical College, Belgam and Kasturba Medical College, Mangalore. At present he is the associate professor of Biochemistry at Father Muller Medical College, Mangalore, and is the Deputy Quality Manager (Quality Management System) of NABL-accredited Father Muller Medical College Hospital Laboratory, Mangalore. Dr. Avinash is a recognized post graduate guide, and he has over 20 research publications to his credit. He is the author of two chapters in internationally published books on “minerals status in Pre menopause and post menopause”. His areas of research are quality assurance in laboratory, automated verification test reports, mineral status in health and disease, and methods for estimation of protein oxidation products.

Mr. Arun Kumar is assistant professor of Biochemistry at Father Muller Medical College, Mangalore. He has vast experience of 20 years in teaching medical and paramedical students, and in management of Clinical Biochemistry Laboratory. He is an alumnus of Manipal University. At present he is pursuing his doctoral studies on “Ischaemia modified albumin” . He is the Deputy technical manager in Biochemistry at NABL-accredited Father Muller Medical College Hospital Laboratory, Mangalore.

Dr. Malathi M. is the Professor and Head of Biochemistry at Father Muller Medical College, Mangalore. She is MBBS, MD (Biochemistry)-qualified professional with 15 years of experience in teaching medical students. She is an alumnus of Manipal University. Dr. Malathi is a recognized post graduate guide and has 10 research papers to her credit. She is the technical manager in Biochemistry at NABL-accredited Father Muller Medical College Hospital Laboratory, Mangalore. She has guided many post graduate and undergraduate students for their research projects, and actively involved in academics, curriculum development and quality management.

Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. from India made a historical victory over the international competition and won Michael Faraday Research Award-2015 in Biochemistry. Their research was highlighted in international media and gathered a large worldwide attention in scientific circles while it appeared in world's most read journal 'International Journal of Biochemistry'. In their report on Urinary Alkaline Phosphatase, Gamma Glutamyl Transferase and Lactate Dehydrogenase in Type 2 Diabetic Nephropathy, and their Correlation with Albuminuria they mention that The present study aimed to assess urinary enzymes in diabetic nephropathy and correlate the changes in enzymes with albuminuria. Urinary levels of enzymes alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) and lactate dehydrogenase (LDH) were assayed in normal healthy controls (group-I), normoalbuminuric type 2 diabetic patients without complications (group-II) and type 2 diabetic patients with microalbuminuria (group IIIa), and macroalbuminuric type 2 diabetic nephropathy patients (group-IIIb). Urinary ALP, GGT and LDH were significantly higher in diabetic patients when compared to controls. Most pronounced increase in urinary enzymes was observed in macroalbuminuric diabetic nephropathy patients, followed by microalbuminuric diabetic nephropathy patients and normoalbuminuric diabetic patients. Urinary enzymes serve as sensitive indicators of renal function in early stages of diabetic nephropathy. Measuring the activities of urinary enzymes could help in diagnosing nephropathy et early stages of type 2 diabetes mellitus, and could also help in follow up of treatment, and preventing macrovascular complications of diabetes mellitus. Considering the non-invasiveness of urine collection, its suitability for repeated sampling, and sensitivity of enzymatic markers, further studies on urinary biomarkers of microvascular complications of diabetes are required. Under their leadership the research area is surely likely to expand beyond the horizons. It will be worthy to explore the further potential under their legacy. Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. as valuable intellectuals for the India offer exclusive opportunities for scholars around the world. One of the most attractive weightage for India is to have the awardees for promotion of the concerned scientific discipline for the benefit of its civilians. Thus India which has excellent track record to produce brain storming intellectuals, has offered a new extension in terms of Laxman Pokhrel, Mohamed Rafi, Shivashankara A.R., Avinash S.S., Arun Kumar K. and Malathi M. to world. Urinary enzymes are sensitive markers of subclinical renal disease in diabetes mellitus, and show significant correlation with albuminuria.

This study focused on urinary enzymes as biomarkers of diabetic nephropathy. There is paucity of studies in this topic, and finding non invasive urinary enzymes along with microalbumin was the highlight of our research. The assays of enzymes were monitored with quality control programme in the laboratory.

Considering the non-invasiveness of urine collection, its suitability for repeated sampling, and sensitivity of enzymatic markers, further studies on urinary biomarkers of microvascular complications of diabetes are required. Future studies with larger sample size, correlating urinary enzymes with glycemic control and albuminuria, are required to establish urinary biomarkers of diabetes and its complications.
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