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International Agency for Standards and Ratings honors Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh with Frederick Banting Research Award-2015 in Pharmacy for great scientific contribution
16 April, 2015, India, USA NEWS CORP
In terms of Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh, India has secured valuable assets for its generations. Nisha Singh, Roshan Issarani, B.P Nagori, Manish Singh and Mamta Singh marked a milestone history while cracking international meritorious competition. India has witnessed World’s 500 Most Influential Pharmacologists for Year 2015 on Earth in terms of Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh. Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh, given new leadership to world, marked history on international level. Nisha Singh, Roshan Issarani, B.P Nagori, Manish Singh and Mamta Singh are awarded with Frederick Banting Research Award-2015 in Pharmacy.
Nisha Singh is Assistant Professor at Department of Pharmacy, Lachoo Memorial College of Science and Technology, Jodhpur, Rajasthan, India.
Roshan Issarani is Head of Department at Department of Pharmacy, Lachoo Memorial College of Science and Technology, Jodhpur, Rajasthan, India.
B.P Nagori is Director at Department of Pharmacy, Lachoo Memorial College of Science and Technology, Jodhpur, Rajasthan, India.
Manish Kumar Singh is Senior Research Scientist at Research Center, Fortis Clinical Research Limited, Faridabad, Haryana, India.
Mamta Singh is Assistant Professor at Department of Pharmacy, Lachoo Memorial College of Science and Technology, Jodhpur, Rajasthan, India.
Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh from India made a historical victory over the international competition and won Frederick Banting Research Award-2015 in Pharmacy. Their research was highlighted in international media and gathered a large worldwide attention in scientific circles while it appeared in world's most read journal 'International Journal of Pharmacy'. In their report on Formulation and in vivo Evaluation of Buccoadhesive Gels Containing Glimepiride: An Antidiabetic Drug they mention that The aim of the present investigation was development and in-vivo evaluation of buccoadhesive gel of an antidiabetic drug i.e., Glimepiride, and to maintain its bioavailability over an extended period of time and to circumvent the hepatic first pass effect. The buccoadhesive gels were prepared using carbopol, hydroxy propyl methyl cellulose, methyl cellulose and sodium carboxy methyl cellulose in different ratios. On the basis of in-vitro studies the formulations GCPH2 and GF16 were selected for in-vivo and stability studies. A maximum hypoglycaemic response was observed at 10 hr and thereafter remained stable up to 24 hr. The formulation GF16 was found stable after stability studies. Under their leadership the research area is surely likely to expand beyond the horizons. It will be worthy to explore the further potential under their legacy. Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh as valuable intellectuals for the country offer exclusive opportunities for scholars around the world. One of the most attractive weightage for India is to have the awardees for promotion of the concerned scientific discipline for the benefit of its civilians. Thus India which has excellent track record to produce brain storming intellectuals, has offered a new extension in terms of Nisha Singh, Roshan Issarani, B.P Nagori, Manish Kumar Singh and Mamta Singh to world.
Among the formulations F-16 (CPH2 + 1% SLS) and GF-16 (GCPH2 + 1% sodium taurocholate), GF16 was more suitable with the objective of the study and acceptable because it maintained the drug release for longer period of time (t50% - >6 hrs.). All the formulation followed Higuchi model release and mechanism was fickian diffusion. In-vivo results revealed that the buccal gels successfully prevented the severe hypoglycemia in the initial hours and showed sustained action as compared to normal and diabetic control. The formulation is easy to scale up as the procedure is simple and do not involve lengthy procedures and unnecessary use of pharmaceutically unacceptable additives. On the basis of stability studies, it was concluded that buccoadhesive gel possess good stability.
Buccoadhesive gels avoids the first pass metabolism thus increases the bioavailability. The formulation maintained the drug release for longer period of time (t50% - >6 hrs.). The formulation is easy to scale up as the procedure is simple.
Similar to other mucosal membranes, the buccal mucosa has some disadvantages including short residence time and small absorption area. Moreover, the dosage form resides in a taste-sensing organ, and organoleptic aspects of formulation could become central and limiting factors for drug application. Suitable palatal properties are often required to improve acceptability of dosage form or to mask less desirable properties of the active component. The major limitation to buccal drug delivery is the barrier property of the tissue. You can share this News URL on Facebook or your Social Media Site/ blog. USA NEW SCORP If you have a news you can Submit your News in Comment box> Join us as Journalist > News Content purchase > Corrections > Copyright > Place a Classified Ad > Sell Your Home > Sell Your Business > Commercial Real Estate Ads > Advertise with us > Recruitment & Career Ads > Franchising > Advertise Locally > Contact us > plojindexing@gmail.com
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